The files provide summary statistics for the GWAS meta-analysis reported in the manuscript "Medical Records-based Genetic Studies of the Complement System"
==========================================================================================

1) C3_Meta_overlapping_marker.txt.gz: Summary statistics for the meta-analysis for the nadir of C3 levels involving N=3,949 eMERGE-III participants across 3 ancestral groups  (European=3210, African=589 and East Asian=150).

2)  C4_Meta_overlapping_marker.txt.gz: Summary statistics for the meta-analysis for the nadir of C4 levels involving N=3,998 eMERGE-III participants across 3 ancestral groups  (European=3,247, African=600 and East Asian=151).

Within each file, the data are presented as follow:
===================================================

rsID: rs identifier 
CHR: chromosome
BP: position (hg19)
A1: Effect allele
A2: Alternative allele
BETA: Beta coefficient for Effect allele
SE: standard error
P: P value